July 12, 2019

Rajiv Shukla
Chief Executive Officer
Constellation Alpha Capital Corp.
Emerald View, Suite 400
2054 Vista Parkway
West Palm Beach, FL 33411

       Re: Constellation Alpha Capital Corp.
           Form 10-K for the Fiscal Year ended March 31, 2019
           Filed June 14, 2019
           File No. 001-38118

Dear Mr. Shukla:

      We have reviewed your filing and have the following comment. In our
comment, we
may ask you to provide us with information so we may better understand your
disclosure.

       Please respond to this comment within ten business days by providing the
requested
information or advise us as soon as possible when you will respond. If you do
not believe our
comment applies to your facts and circumstances, please tell us why in your
response.

       After reviewing your response to this comment, we may have additional
comments.

Annual Report on Form 10-K for the fiscal year ended March 31, 2019

Constellation Alpha Capital Corp.
Notes to Financial Statements
Reconciliation of net loss per ordinary share, page F-10

1.     In the reconciliation of net loss per ordinary share, you reflect an
adjustment for income
       attributable to ordinary shares subject to redemption. Please explain in
further detail how
       you calculated or determined the amount of this adjustment for each
period presented.
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.
 Rajiv Shukla
Constellation Alpha Capital Corp.
July 12, 2019
Page 2

       You may contact Linda Cvrkel at 202-551-3813 or Craig Arakawa at
202-551-3650 if
you have questions regarding comments on the financial statements and related
matters. Please
contact Michael Killoy at 202-551-7576 or Pam Howell at 202-551-3357 with any
other
questions.



                                                          Sincerely,
FirstName LastNameRajiv Shukla
                                                          Division of
Corporation Finance
Comapany NameConstellation Alpha Capital Corp.
                                                          Office of Beverages,
Apparel and
July 12, 2019 Page 2                                      Mining
FirstName LastName